Publications

Huynh V, Wylie RG (2019) Displacement affinity release of antibodies from injectable hydrogels. ACS Applied Materials and Interfaces. DOI: 10.1021/acsami.9b12572

Huynh V, D'Angelo A, Wylie RG (2019) Tunable degradation of low-fouling carboxybetaine-hyaluronic acid hydrogels for applications in cell encapsulation. Biomedical Materials. DOI: 10.1088/1748-605X/ab2bde

Shoaib MM, Huynh V, Shad Y, Ahmed RT, Jesmer AH, Melacini G, Wylie RG. (2019) Controlled degradation of low-fouling poly(oligo(ethylene glycol)methyl ether methacrylate) hydrogels. RSC Adv. DOI: 10.1039/c9ra03441b

Ahmed RT, Akcan M, Khondker A, Rheinstadter M, Bozelli Jr J, Epand RM, Huynh V, Wylie RG, Boulton S, Huang J, Vershoor C, Melacini G (2019) Atomic resolution map of the soluble amyloid beta assembly toxic surfaces. Chem. Sci.  DOI: 10.1039/C9SC01331H

Huynh V, Jesmer AH, Shoaib MM, Wylie RG. (2018) Influence of hydrophobic crosslinkers on carboxybetaine copolymer stimuli response and hydrogel biological properties. Langmuir DOI: 10.1021/acs.langmuir.8b03908

Huynh V, Jesmer AH, Shoaib MM, D'Angelo A, Rullo AF, Wylie RG. (2018) Improved efficacy of antibody cancer immunotherapeutics through local and sustained delivery. Chembiochem DOI: 10.1002/cbic.201800579

Choudhuri K, de Silva UK. Huynh V, Wylie RG, Lapitsky Y. (2018) Photolithgraphically assembled polyelectrolyte complexes as shape-directing template for thermoreversible gels. J. Material Chem. B. DOI: 10.1039/C8TB02104J

McAlvin J, Wylie RG, Ramchander K, Nguyen M, Lok C, Moroi M, Shomorony A, Vasilyev N, Armstrong P, Yang J, Lieber A, Okonkwo S, Karnik R, Kohane D. (2018) Antibody modified conduits for highly selective cytokine elimination from blood. JCI Insight 3(13):e121133.

Lambert C, Nijsure D, Huynh V, Wylie RG. (2018) Hydrogels with reversible chemical environments for in vitro cell culture. Biomedical Materials 13, 4.

Huynh V, Wylie RG. (2018) Competitive Affinity Release for Long Term Delivery of Antibodies from Hydrogels. Angewandte Chemie Int Ed 130 (13), 3406-3410.

Before McMaster

McAlvin JB, Wylie RG, Ramchander K, Nguyen MT, Lok CK, Moroi M, Shomorony A, Vasilyev NV, Armstrong P, Yang J, Lieber AM, Okonkwo OS, Karnik R, Kohane DS (2018) Antibody-modified conduits for highly selective cytokine elimination from blood. JCI Insight 3 (13), e121133.

Lim DK*, Wylie RG*, Langer RS, Kohane DS. (2015) Antiangiogenic Bioactive Polymer: Selective Binding Properties of C-6 OH Sulfated HA to VEGF165a. Biomaterials 77, 130-138.

 

Wang W*, Liu Q*, Zhan C, Barhoumi A, Yang T, Wylie RG, Armstrong PA, Kohane DS. (2015) Efficient Triplet–Triplet Annihilation-Based Upconversion for Nanoparticle Phototargeting. Nano Letters 15 (10), 6332-6338.

 

Lim DK., Barhoumi, A., Wylie, RG, Langer, RS, Kohane, DS. (2013) Enhanced Photothermal Effect of Plasmonic Nanoparticles Coated with Reduced Graphene Oxide. Nano Letters 13 (9), 4075-4079.

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Wylie RG, Shoichet MS. (2011) Three-dimensional spatial patterning of proteins in hydrogels. Biomacromolecules. 12, (10) 3789-3796.

 

Wylie RG, Ashan S, Maxwell KL, Morshead CM, Shoichet MS. (2011)

Three-dimensional, spatially controlled simultaneous patterning of

multiple growth factors in hydrogels. Nature Materials. 10 (10), 

799-806. (Cover; featured in news and views of Nature Materials

Vol. 10 No.10, 2011)

 

Leipzig ND, Wylie RG, Kim H, Shoichet MS. (2011) Differentiation of neural stem cells in three-dimensional growth factor-immobilized chitosan hydrogel scaffolds. Biomaterials 32 (1) 57-64.

 

Wang Y, Cooke MJ, Lapitsky Y, Wylie RG, Sahewsky N, Corbett D, Morshead CM, Shoichet MS. (2011) Transport of epidermal growth factor in the stroke-injured brain. Journal of Controlled Release. 149 (3), 225-235.

 

Aizawa Y, Wylie RG, Shoichet MS. (2010) Endothelial Cell Guidance in 3D Patterned Scaffolds. Advanced Materials. 22 (43), 4831-4835.

 

Rahman N, Purpura, KA, Wylie RG, Zandstra PW, Shoichet MS. (2010) The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells. Biomaterials. 31 (32), 8262-8270.

 

Taerum T, Lukoyanova O, Wylie RG, Perepichka, DF. (2009) Synthesis, Polymerization, and Unusual Properties of New Star-Shaped Thiophene Oligomers. Organic Letters. 11 (15), 3230-3233.

 

Wylie RG, Shoichet, MS. (2008) Two-photon micropatterning of amines within an agarose hydrogel. Journal of Materials Chemistry 18 (23), 2716-2721. 

Book Chapters

Lévesque, S.; Wylie, RG; Aizawa, Y.; Shoichet, M.S. (2008) “Peptide Modification of Polysaccharide Scaffolds for Targeted Cell Signaling" in Handbook of Natural-based Polymers for Biomedical Applications, Ch. 9, pp. 260-87, edited by R.L. Reis, Woodhead Publishing Ltd, UK.

Patents

Huynh V, Wylie R.G. Canadian Patent Application, June 2017 “Affinity Based Drug Release System” (Filed) 17-002, 3244-P51101CA00

 

Huynh V, Wylie R.G. U.S Provisional Patent Application, June 2016 “Affinity Based Drug Release System” (Filed) 62/345,958

 

Wylie, R.G.; Kohane D.S. U.S. Provisional Patent Application, Oct 2015 “Sustained and Reversible oral drug delivery systems” (Filed) PCT/US2015/056469

Wosnick, J.; Wylie, R.G.; Shoichet, M.S. Canadian Provisional Patent Application, 2014 "Three-Dimensional Patterned Hydrogels" (Filed)

 

McAlvin, B.; Wylie, R.; Mizrahi, B.; Kohane, D.S. U.S. Provisional Patent Application, 2013 “Systems and Methods for Extracorporeal Blood Modification” (Filed)

 

Wosnick, J.; Wylie, R.G.; Shoichet, M.S. U.S. Patent, 2008 "Three-Dimensional Patterned Hydrogels" Patent Pub. No. 2008/028630 (Granted)